• Cannabis produced has a Trichomes density of up to 200 times greater than in a plant-grown product while solving major industry challenges of consistency, safety, and environmental sustainability
• The Company is ready to engage with key players in the global Cannabis industry

VANCOUVER, CANADA, AND REHOVOT, ISRAEL, December 8, 2021 – BioHarvest Sciences Inc.(“BioHarvest” or the “Company”) (CSE: BHSC) has announced that it has produced a meaningful amount (10 kilograms) of full-spectrum Cannabis biomass at a commercial scale without growing the plant itself. (For full illustration, watch the “Cannabis Without Plants – History in the Making” video at https://youtu.be/NAurl6oa1xo)

It is the first time that any group – in either industry or academia – has successfully produced meaningful quantities of full-spectrum Cannabis biomass without growing the plant itself. The Cannabis biomass is not genetically modified and was produced using the Company’s proprietary BioFarming technology platform, which grows plant cells in their natural structure in proprietary bioreactors.

The result of the breakthrough by the Canadian-Israeli biotech firm is Cannabis biomass that is uniquely consistent and clean, resolving two major pain points related to product quality in the medicinal Cannabis industry. Namely – product variability and product contamination.

“The legal Cannabis industry has been waiting for this moment as many of the challenges it has faced are being resolved using BioHarvest’s technology and capabilities,” said BioHarvest CEO Ilan Sobel. “With this milestone, we are ready to start engaging with key players in the global Cannabis industry for the right partnerships ahead of the introduction of our new Cannabis products.”

The biomass consists of Cannabis cells, including Cannabis Trichome cells containing Cannabinoids such as CBD, THC, as well as other compounds that are naturally occurring in the Cannabis plant. BioHarvest’s Cannabis Trichome cells are amalgamated in a proprietary high-density coral-shaped structure, which enables a Trichome density (number of trichomes per unit surface) of up to 200 times greater than the conventional agriculture case.

The result is a win for global sustainability, ushering in a new era by conserving land not just from Cannabis cultivation but that of other plants. BioHarvest is already achieving this with red grapes, olives, and pomegranates. BioHarvest’s production facilities use some 95% less physical space than traditional farming; for reference, one seven-foot bioreactor produces what would require 240,000 square meters of land annually for the production of the key polyphenols contained in its red grape VINIA® product.

The Cannabis biomass produced by BioHarvest’s technology has significant advantages compared to Cannabis produced through conventional cultivation, summed up by what the Company refers to as the 5 Cs:

1. Consistency: Critical for medicinal Cannabis and any pharmaceutical application as well as for large-scale application to major brands in the food and beverage industry.
2. Cleanliness: The aseptic and highly controlled environment means no fungi, yeast, or mold, or any other contamination source, no pesticides, and no requirement for irradiation of the product.
3. Cost: A significant reduction in the production costs, resources, and time required versus indoor and greenhouse Cannabis cultivation.
4. Composition: Full spectrum in the original molecular conformation, allowing to optimize bioavailability.
5. Climate: Third-party assessments confirm BioHarvest’s growing process generates no direct greenhouse gas emissions and no hazardous waste, and only produces 100% biodegradable wastewater while requiring less than 10% of the land resources and significantly less energy when compared to conventional cultivation.

“For its therapeutic qualities, Hemp-based CBD holds a significant potential for the F&B industry to which we have been supplying ingredients for over 40 years,” said Vince Pinneri, President of Batory Foods, a leading ingredient distributor for the US food industry. “That is why we decided to team up with BioHarvest in order to guarantee the F&B industry the highest quality CBD with fingerprint consistency and ultimate cleanliness that their BioFarming technology can produce. The outstanding sustainability credentials of the BioFarming technology will also be well received by the growing population of environmentally conscientious customers. We are looking forward to bringing to the US market the best hemp-based CBD, from BioHarvest, in the near future.”

BioHarvest has a market capital of about CAD$ 152M and has raised about CAD$ 57.3M to date. The Company’s next stage will consist of producing Cannabis biomass in industrial-scale bioreactors. Its offering will consist of multiple strains, carefully selected based on specific indications and B2B customer requirements.

“This major scientific and technological achievement is unprecedented in the Cannabis world and is a strong validation of the superiority of the BioFarming technology,” said CTO Yochi Hagay. “BioHarvest’s global leadership position in plant cell biology is proving itself now on a wide variety of applications.”

Reflecting the breadth of possible applications, earlier this month, BioHarvest appointed renowned astronaut Chris Hadfield to its board of advisors as part of a drive to leverage its biotechnology platform to create products that address the challenges of space exploration. Christ Hadfield joined the BioHarvest board several weeks after a visit to the Company’s laboratories in Rehovot, Israel, when he spent several hours with the Company’s scientists.

Among other examples, BioHarvest’s BioFarming technology can produce primary metabolites that amount to food for humans in space. It also can produce antioxidant compounds that can relieve human cellular stress and damage caused by microgravity and ionizing radiation.

About BioHarvest Sciences Inc.

BioHarvest Sciences Inc. (CSE: BHSC) is a fast-growing Biotech firm listed on the Canadian Securities Exchange. BioHarvest has developed a patented bio-cell growth platform technology capable of growing the active and beneficial ingredients in fruit and plants, at industrial scale, without the need to grow the plant itself. This technology is economical, ensures consistency, and avoids the negative environmental impacts associated with traditional agriculture. BioHarvest is currently focused on nutraceuticals and the medicinal cannabis markets. Visit: